Blunting of vaccine responses has been observed in IgG-antibody concentrations to different pertussis vaccine antigens, specifically, pertussis toxin, filamentous hemagglutinin, and pertactin, and ...

Structural basis for neutralizing antibody binding to pertussis toxin Go to source). The Resurgence of Whooping Cough Whooping cough, also known as pertussis, is making an alarming comeback.

Among infants born to tetanus toxoid–immunized mothers, postvaccination GMCs of anti–pertussis toxin IgG at 9 months were twice as higher in those who received DTwP vaccines than in those who ...

TOPLINE: A booster dose of recombinant pertussis vaccines provides sustained immunity in adolescents and young adults even after 5 years, with pertussis toxin (PT)–neutralizing antibody levels ...

Since the 1990s the U.S. has instead used what’s called an acellular vaccine, which includes only a handful of the bacterium’s components, such as surface proteins or the pertussis toxin.

DTaP vs. Tdap. Both vaccines contain inactivated forms of the toxin produced by the bacteria that cause the three diseases. Inactivated means the substance no longer causes disease but does ...

The pertussis toxin can trigger a reaction that produces a high white blood cell count, Yeganeh said — potentially causing sludging in the blood vessels leading to the lungs.

Pertussis infections have surged in recent months, and some people may need an additional shot for protection. By Teddy Rosenbluth After a brief lull during the pandemic, whooping cough has ...