Podocytes demonstrate a strong reliance on insulin to function properly, according to a study published in Cell Metabolism (2010;12:329-340).

A newly-established protocol offers hope for kidney disease modeling, drug discovery, and potential cell therapies. Previous work from the Wyss Institute at Harvard University established a protocol ...

Image of the Day: Purple Podocytes. Using human induced pluripotent stem cells, scientists grew podocytes, cells that attach to the kidney's glomeruli and help filter blood. The Scientist. The ...

Kidney podocytes, all grown up New protocol produces large numbers of mature human podocytes Date: July 11, 2018 Source: Wyss Institute for Biologically Inspired Engineering at Harvard ...

Podocytes are specialised cells of the renal corpuscles (glomeruli) that play a crucial role in the filtering function of the kidney. Their size and density are important indicators of the health ...

A new research paper was published in Aging's Volume 15, Issue 14, entitled, “Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span.” ...

Injury of podocytes, if recognized at all, has been considered a late consequence caused by increasing proteinuria rather than an event inciting diabetic nephropathy.

Abatacept (CTLA-4–Ig) is an inhibitor of the T-cell costimulatory molecule B7-1 (CD80). 3 B7-1 is induced in podocytes in various animal models of proteinuria. 4 Podocyte B7-1 expression is not ...

More information: Natalya Kaverina et al, Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span, Aging (2023). DOI: 10.18632/aging.204897 ...

The gene therapy, called PS-002, uses a modified virus to treat kidney cells called podocytes. Administration of PS-002 in a mouse model of IgA nephropathy reduced signs of kidney dysfunction, ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, “Inhibiting NLRP3 signaling in aging ...