Background: iza-bren is a first-in-class ADC comprised of an EGFR x HER3 bispecific antibody conjugated to a novel topo-I inhibitor payload (Ed-04) via a stable tetrapeptide-based cleavable linker.

Site-selective modifications of proteins, without compromising their biological activity, are highly sought after due to their critical role in many biomedical applications. Here, we established a ...

In this issue of The Lancet Oncology, another phase 2 trial conducted exclusively in China with a different HER2-targeted antibody–drug conjugate as the palliative second-line treatment of NSCLC is ...

Introduction -- Verb conjugated with avoir or etre to from a compound tense -- Formation of the present and past participles in French -- Principal parts of some important verbs -- Tables showing ...

Many polycyclic aromatic hydrocarbons (PAHs) in the environment resulting from crude oil spills and the incomplete combustion of organic matter are highly toxic, mutagenic, or carcinogenic to ...

1 Introduction Conjugate strike-slip faults are one of three typical types of faults in the Anderson fault model (Anderson, 1905; 1942) and are given a special definition (Twiss and Moores, 1992; ...

The consecutive tenses are fundamental in all descriptions of Classical Hebrew grammar. They are even basic to the textbooks on Biblical Hebrew. Being fundamental in the verbal system, and part of any ...