Discussion The expression of a primary cilium relies on two main events: 1) activation of ciliogenesis and 2) orderly progression through a series of developmental stages so that a structurally ...

More information: Yu Xun et al, GPR45 modulates Gα s at primary cilia of the paraventricular hypothalamus to control food intake, Science (2025). DOI: 10.1126/science.adp3989 ...

The transition from primary to secondary school is a critical period in a young person’s educational journey, marked by substantial shifts in academic expectations, social dynamics and emotional ...

Railway track transition zones represent critical segments where structural and material properties change abruptly, such as at the interface between ballasted and ballastless (slab) tracks or ...

Residents in a tree-lined Christchurch street are rallying against a multi-unit housing complex they say could ruin the area. A developer has bought an 857 square metre section on Somerfield's ...

Fisher East includes multiple zones grading above 2.0% nickel, allowing for flexible mine sequencing and margin protection in volatile nickel price cycles.

Human Cilia Disease Cilia are ubiquitous hair-like organelles that form specialised cell compartments, extending out from the surface of most cells in the body with an internal microtubular axoneme ...

The shear mechanical compliance of the glass−rubber transition or softening zone of high molecular weight amorphous polymers typically increases from the glassy compliance of ∼10−10 cm2/dyn up to the ...

Phosphorylation at the elbow of OSM-3 is inhibitive in vivo (A) Representative images of the phospho-dead (PD) and phospho-mimic (PM) knock-in worms showing their OSM-3 signal at amphid cilia, amphid ...