A team at the Peter Mac is planning for first-in-human trials in five years, hoping this new therapy will eschew the ...

Cis-regulatory elements (CREs)—including promoters, enhancers, silencers, and insulators—are critical non-coding DNA ...

The FDA’s Orphan Drug Designation offers incentives like seven years of U.S. market exclusivity, tax credits for clinical ...

Shares of Klotho Neurosciences, Inc. (NASDAQ:KLTO) surged 22% following news that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to the company’s gene therapy ...

The U.S. FDA has granted orphan drug designation to Klotho Neurosciences Inc.’s secreted-Klotho (s-KL) promoter, gene and ...

This study demonstrates that Setd2 overexpression rescues bivalent gene expression during zygotic genome activation (ZGA) in ...

Actinomycetes are important organisms for the biosynthesis of valuable natural products. However, only a limited number of well-characterized native constitutive promoters from actinomycetes are ...

a, Co-transfection of an ARF promoter-driven reporter plasmid containing two Gal4-binding sites with Gal4-Rb or Gal4-DNMT1 into HCT116 cells results is repression of reporter gene activity.

More than three decades after the rape of a 12-year-old girl, investigators say DNA evidence allegedly links a Brockton man to the assault.

A deep-learning model trained on human data reveals that promoter mutations may explain a significant portion of unsolved ...