Imagine the magnificent glaciers of Greenland, the eternal snow of the Tibetan high mountains, and the permanently ice-cold ...

Rational drug design depends on the knowledge of the three-dimensional (3D) structure of complexes between proteins and lead compounds of low molecular weight. A novel nuclear magnetic resonance (NMR) ...

Essentially, cereblon and its target proteins can change shape to form a complex with the cereblon, the target, and the ...

The findings from this landmark publication, featured on the cover of Science, have accelerated our ability to develop first-in-class medicines for historically intractable targets, validating the ...

A better understanding of human smell is emerging as scientists interrogate its fundamental elements: the odor molecules that ...

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living cells - using the cells' own components as built-in sensors.

Learn how cell-free protein synthesis helps researchers overcome the challenges of traditional membrane protein production ...

Researchers have found a new way to optimise the design molecular motors, bringing us one step closer to making synthetic molecular machines a reality ...

While biopharmaceutical technologies have made substantial strides in treating diseases, drug research and development ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living ...