Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of ...

In 1998, Andrew Fire and Craig Mello published a groundbreaking study demonstrating that double-stranded RNA (dsRNA) could silence genes in the nematode Caenorhabditis elegans. This discovery laid the ...

RNA interference (R Contract service = outsourced research/target validation projects Total = Projected worldwide RNAi revenues for 2010, in US dollars Source: Frost & Sullivan Scientists hunger for ...

[28] RNA interference (RNAi) is a naturally occurring biological pathway in which small, double-stranded RNA molecules suppress gene expression in an exquisitely sequence-specific manner Exogenous ...

The secondary structure of the mRNA target site has ... Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494–498 (2001).

RNA interference (RNAi) acts like a "gene switch," selectively silencing specific genes. It uses specialized RNA molecules, such as small interfering RNA (siRNA) or microRNA (miRNA), to block ...

With small molecules, which make up an estimated 90% of approved medicines 1, each new medicine requires in-depth knowledge of the structure ... an approach called RNA interference (RNAi) are ...