The secondary structure of the mRNA target site has ... Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494–498 (2001).

a phenomenon called RNA interference or RNAi. The apparently widespread nature of RNAi in eukaryotes, ranging from trypanosome to mouse, has sparked great interest from both applied and ...

[28] RNA interference (RNAi) is a naturally occurring biological pathway in which small, double-stranded RNA molecules suppress gene expression in an exquisitely sequence-specific manner Exogenous ...

In 1998, Andrew Fire and Craig Mello published a groundbreaking study demonstrating that double-stranded RNA (dsRNA) could silence genes in the nematode Caenorhabditis elegans. This discovery laid the ...

Our group retains an interest in the areas of structure-function studies of RNA interference mediated by siRNA pathway, and on post-translation histone and DNA modifications impacting on epigenetic ...

RNA interference (R Contract service = outsourced research/target validation projects Total = Projected worldwide RNAi revenues for 2010, in US dollars Source: Frost & Sullivan Scientists hunger for ...

Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of ...