The oxidation state of mitochondria was also verified in a second line of mice, one with lower mito-roGFP expression levels (Supplementary Fig. 7), and in cultured cells expressing mito-roGFP ...

However, the roGFP probe is sensitive to a different range of oxidation-reduction potentials than our FRET probe, possibly leading to complementary applications." ...

A multidisciplinary research team within the Institute for Genomic Biology at the University of Illinois, Urbana-Champaign reports a FRET-based biosensor with defined sensitivity and dynamic range ...

The roGFP also included a sequence that targeted the protein to mitochondria. Since roGFP lights up when oxidized, the protein provided a way to directly visualize the oxidation state of mitochondria.

To demonstrate the practical application of these PNCs, the researchers utilized a reduction-oxidation (redox) sensitive green fluorescent protein (roGFP) as a model cargo. This protein acts as a ...

In work published in the June 2011 issue of Experimental Biology and Medicine, Kolossov, Spring and their co-investigators - a multidisciplinary team within the Institute for Genomic Biology at ...

A multidisciplinary research team within the Institute for Genomic Biology at the University of Illinois, Urbana-Champaign reports a FRET-based biosensor with defined sensitivity and dynamic range for ...