Rationale: Macrophages are critically involved in wound healing following myocardial infarction (MI). Lgr4, a member of LGR (leucine-rich repeat-containing G protein-coupled receptor) family, is ...

The NOX-targeted therapy market is expected to expand significantly over the upcoming years as more therapies move into late-stage developmen ...

The heart is a never-stopping engine that relies on a formidable pool of mitochondria to generate energy and propel pumping. Because dying cardiomyocytes cannot be replaced, this high metabolic rate ...

Recently, there has been a better understanding about the ontogeny, phenotype and function of alveolar macrophages and their role, not only in phagocytosis, but also in initiating and resolving immune ...

Immune disorders are intimately involved in the pathological progression of myocardial ischemia–reperfusion injury (MIRI) and exacerbate cardiac cell damage and mitochondria-related metabolic ...