In severe cases of tissue death, there’s a possibility of amputation. This is commonly performed on arms, legs, fingers, or toes . Calciphylaxis isn’t curable, but remission is possible.

This month, the Food and Drug Administration approved the first therapy for treatment of severe frostbite in the country. This month, ...

The FDA on Wednesday approved the first medication injection to treat severe frostbite. Aurlumyn, which has the active ingredient iloprost, reduces the risk of finger or toe amputation, the FDA said.

It has been shown that below-knee amputations can heal by first intention in patients with severe arterial insufficiency, 1,2 but failure of healing has been reported in the majority of patients ...

Activation and targetability of TYMP–IL-6–TF signaling in the skin microenvironment in uremic calciphylaxis. Science Translational Medicine , 2025; 17 (795) DOI: 10.1126/scitranslmed.adn5772 ...

Severe Frostbite Gets a Treatment That May Prevent Amputation The F.D.A. recently approved the first therapy for patients in danger of losing their toes, fingers and other exposed parts of the ...

The first time Dr. Peter Hackett saw a patient with frostbite, the man died from his wounds. It was in Chicago in 1971, and the man had gotten drunk and passed out in the snow, his fingers so froze… ...

News; Nation/World; Severe frostbite gets treatment that may prevent amputation Feb. 24, 2024 Updated Sat., Feb. 24, 2024 at 6:41 p.m. New Zealand climber Mark Inglis, a double-amputee, shows the ...