Around 2,500 people are living with sickle cell disease in the Bay State, and they are advocating for a bill that would improve quality of life for all those dealing with the disease.

The first healthy volunteer has been dosed in a Phase 1 study of Cellarity's novel globin-switching therapy CLY-124 for ...

Look inside a brain cell with Huntington's disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up ...

Sickle cells clump together, blocking small blood vessels and causing painful and damaging problems. SCD is treated with pain medicines as needed, drinking 8 to 10 glasses of water each day, blood ...

Sickle cell disease affects only adult hemoglobin, causing it to clump and distort red blood cells into a sickle shape. Preserving fetal hemoglobin after birth at levels above 8% through gene editing ...

Sickle cell disease is a genetic blood disorder characterised by the production of abnormal haemoglobin, which causes red blood cells to become rigid and sickle-shaped. These cells tend to clump ...

In sickle cell disease, this adult haemoglobin does not work properly, red blood cells are sickle shaped and can get stuck in blood vessels. Thus, the disease symptoms begin to emerge when children ...

Living with sickle cell disease means navigating the unpredictability of pain crises – those sudden, excruciating episodes that often lead to emergency room visits. For patients and their ...

Those with sickle cell disease have cells shaped like a banana or a “sickle,” an old farm tool. The cells are unable to move as freely and can clump together, blocking blood flow to parts of the body.

Sickle cell participants with older-looking brains also scored lower on cognitive tests. The study also found that socioeconomic status correlates with brain age.

However, in sickle cell disease, these RBCs are not round but instead resemble bananas, breaking down much faster than normal. When these red blood cells break down, they leave behind a byproduct ...