When thinking about the benefits of exercise, most people picture stronger muscles, a healthier heart, or weight loss. But ...

Metabolic dysfunction-associated steatotic liver disease (MASLD) affects nearly one in three adults around the globe. It ...

Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But ...

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

The RNA-binding protein IGF2BP1 has emerged as a key regulator of cancer hallmarks, influencing tumor proliferation, metastasis, immune evasion, and ...

Scientists are unraveling the secrets behind insect flight, revealing the complex mechanics of their wing hinges. Caltech researchers, led by Professo ...

Credit: Anna M. Dowbaj, Aleksandra Sljukic et al. Nature (2025) / MPI-CBG The liver has a unique structure, especially at the level of individual cells.

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile ...

University of Tokyo scientists revealed that obesity disrupts the timing of liver metabolism during starvation, without affecting the network’s structure, offering new insight into how our bodies ...

In the short term, these multi-zonal liver organoids will help scientists shed new light on diseases including diabetes, drug-induced liver injury, alcohol-related liver disease, and viral hepatitis.