The discovery may explain why cutting edge CAR T-cell therapy has managed to revolutionized treatment for blood cancer but ...

Comprehensive biomarker testing can identify EGFR or other mutations in your lung cancer. Learn the benefits of testing and how it can help shape treatment.

“For people living with advanced NSCLC harbouring EGFR mutations, new treatment options are urgently needed in the first-line setting,” said Enriqueta Felip, M.D., Ph.D, head of the thoracic ...

Lazcluze in combination with Rybrevant has been approved for first-line Tx of locally advanced or metastatic non-small cell lung cancer ...

The combination is now approved in the frontline for locally advanced or metastatic NSCLC with EGFR exon 19 deletions or exon 21 L858R substitution mutations.

Other mutations are Val690Met and Val968Met. In Mediterranean peoples, the most common mutation is a C563T substitution resulting in an amino acid change (Ser188Phe).

Rybrevant is approved in the US in combination with Lazcluze (lazertinib) for the first-line treatment of adult patients with locally advanced or metastatic NSCLC with EGFR exon 19 deletions or L858R ...

The first-line combination of amivantamab-vmjw plus lazertinib extended OS compared with osimertinib for patients with EGFR-mutated advanced non-small cell lung cancer, according to data from the ...

Rybrevant is approved in the US, Europe and other markets around the world in combination with Lazcluze (lazertinib) for the first-line treatment of adult patients with locally advanced or metastatic ...

Johnson & Johnson JNJ said Tuesday the U.S. Food and Drug Administration has approved a combination treatment for a type of lung cancer that’s the first chemotherapy-free regimen. The FDA has ...

Osimertinib (Tagrisso, AstraZeneca) is indicated for 'adjuvant treatment following complete tumour resection in adults with stage IB to IIIA NSCLC whose tumours have EGFR exon 19 deletions or exon 21 ...

Data show that the recently approved combination of Lazcluze (lazertinib) plus Rybrevant (amivantamab-vmjw) can fill that need for patients with locally advanced (spread nearby) or metastatic (spread ...