The discovery may explain why cutting edge CAR T-cell therapy has managed to revolutionized treatment for blood cancer but ...

A rare genetic mutation in a European sperm donor has reportedly caused cancer in 10 children, highlighting the need for improved genetic screening and family limits in sperm donation.

In this paper, the Shannon capacity of DNA data embedding is obtained for the case in which DNA sequences are subject to substitution mutations modeled using the Kimura model from molecular evolution ...

The first-line combination of amivantamab-vmjw plus lazertinib extended OS compared with osimertinib for patients with EGFR-mutated advanced non-small cell lung cancer, according to data from the ...

Furthermore, tracking these mutations in the spike protein during various phases of vaccine administration across countries could provide insights into the evolution of SARS-CoV-2 mutations and ...

Focusing on the mutational fitness of C→U, the most common type of substitution, I describe C→U substitutions at basepaired positions that characterize major SARS-CoV-2 variants; such mutations may ...

If you want to build a foundational understanding of genomics in both health and disease, it's important to be able to distinguish between the different type of genetic mutations that can occur. Here, ...

Comprehensive biomarker testing can identify EGFR or other mutations in your lung cancer. Learn the benefits of testing and how it can help shape treatment.

Amivantamab plus chemo is now indicated in locally advanced or metastatic NSCLC with EGFR exon 19 deletions or exon 21 L858R substitution mutations after disease progression on or after an EGFR-TKI.

The FDA has approved amivantamab-vmjw (Rybrevant) in combination with standard chemotherapy to treat non–small cell lung cancer (NSCLC) with EGFR exon 19 deletions or exon 21 L858R substitution ...

The Food and Drug Administration approved frontline Lazcluze plus Rybrevant for locally advanced or metastatic non-small cell lung cancer with an EGFR exon 19 deletions or exon 21 L858R substitution ...