There, the vesicles fuse to the surface of the pre-synaptic terminal and release their passengers—the neurotransmitters—into the synaptic space between the neurons.

Similarly, in the pre-synaptic terminal, vesicles unable to carry neurotransmitters might be the cause of neuronal diseases. Therefore, the ability to track these vesicles might reveal important ...

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses.

During clathrin-mediated endocytosis, adaptor proteins bind to the cell membrane and to the protein clathrin, assisting in ...

Coat proteins of vesicles involved in intracellular membrane trafficking have closely related molecular architectures. The structure of COPI extends known similarities, and strengthens the case ...

A small conventional terminal (purple) is shown for comparison. Right) Diagram of synaptic vesicles cycle, showing vesicles fusion and retrieval events, and vesicle distribution and movements in ...

Therefore, before the action potential even arrives at the presynaptic terminal, vesicles containing neurotransmitter line up in a fusion-ready state at docking sites in the presynaptic terminal.

Those two cases may suggest a need to consider hemospermia as a rare symptom of metastatic malignant melanoma to the seminal vesicles although we overall believe that most cases of hemospermia are ...

While the release of neurotransmitters from vesicles is speedy, we always thought vesicle formation was slow. It turns out that vesicle formation can zip along much faster than we thought.