Targeted cancer drugs known as CDK4/6 inhibitors have improved outcomes for patients with advanced or metastatic HR+/HER2- ...

Patients with ID receiving TNF inhibitors are at greater risk for cutaneous malignancy than patients who are biologic-naïve.

Inflammatory mediators like cytokines and chemokines play a key role in driving age-related and postmenopausal breast cancer progression and immune system changes.

Age-related and postmenopausal breast cancer progression remains a significant challenge, with growing evidence pointing to the role of pro-inflammatory cytokines and CXC chemokines in tumor ...

ASCO 2025 overall survival data bolster IMNN-001’s potential in advanced ovarian cancer, supported by robust translational results at ESMO Results from OVATION 2 Study reinforce IMNN-001 mechanism of ...

Role of transcription factor SOX30 in triple-negative breast cancer metastasis and tumor immune microenvironment through the TNF/TNFR2-NF-κB-CCL20/CCR6 axis. Authors: Pingping Gao, Ning Yang, Na Sun, ...

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting ...

Cancer remains a serious health threat within society, with 18 million new cancer cases occurring worldwide in 2020. While novel and more effective treatments continue to increase at a rapid rate, ...

Cancer remains a serious health threat within society, with 18 million new cancer cases occurring worldwide in 2020. While novel and more effective treatments continue to increase at a rapid rate, ...

According to a new report, the global Tumor Microenvironment Market will grow from US$ 1.47 Billion in 2023 to US$ 3.43 billion by 2030 at a compounded annual growth rate (CAGR) of 12.9% during the ...

Secreted factors from M1 macrophages drive prostate cancer stem cell plasticity by upregulating NANOG, SOX2 , and CD44 through NFκB-signaling. OncoImmunology, 2024; 13 (1) DOI: 10.1080/2162402X ...

These tumor microenvironment actuated T cells restricted expression of the GD2 CAR to tumor tissue, preventing fatal neurotoxicity while maintaining anti-tumor efficacy. We also found that conditional ...