In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium ...

By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of ...

Chimeric GyrB–VEGFR-1 and -2 both activate the ERK pathway in PAE cells, (a) PAE cells expressing the GyrB-VEGFR-1 chimera (PAE/GYR.R1), or the GyrB-VEGFR-2 chimera (PAE/GYR.R2) were stimulated ...

Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

When the macrophages’ ability to consume dying cancer cells or Upd3 production was decreased, tumor growth was significantly ...

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

Targeted Oncology connects oncology professionals with updates on immunotherapy, biomarkers, cancer pathways, and targeted ...

DALLAS, June 17, 2025 /PRNewswire/ -- Batbox, the sportstainment brand known for reimagining baseball through immersive play, today announced its transformation into a global sports technology ...

PI3Kγ signaling controls trafficking of CD8 + T cells between lymphoid and non-lymphoid organs and drives hypertension in a murine model The activation and infiltration of immune cells to the ...

On the other hand, peptide mimics represent a safe and viable therapeutic goal for blocking aberrant signaling pathways. The VEGF peptide mimic strategy involves direct binding to the VEGFR-2 ...