Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.

Oncogenic YAP accelerates S-phase entry by shortening G1, leading to replication stress and sensitivity to CHK1 inhibition.

Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

Background Proliferative lupus nephritis (LN) is characterized by robust glomerular and tubulo- interstitial inflammation, sub-endothelial deposits of immunoglobulin, and increased endothelial cell ...

1 Department of Clinical Pharmacy, Xiangtan Central Hospital, Xiangtan, Hunan, China 2 Department of Pharmacy, Xiangtan Central Hospital, Xiangtan, Hunan, China FIGURE 1. Potential signaling pathways ...

Bridging conduits (BC) are tubular protrusions that facilitate cytoplasm and membrane exchanges between tethered cells. We now report that the human immunodeficiency virus type I (HIV-1) exploits ...

This strategy for the treatment of vascular insufficiency was based on the concept of therapeutic angiogenesis. Studies using animal models of peripheral ischemia have demonstrated that vascular ...