Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

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Brandon Aiyuk was asked to assess himself today in the 49ers locker room. Here's what he said. Q: How do you feel about your route running and ho ...

DL Nick Bosa, WR Brandon Aiyuk and LB Fred Warner shared the team's mindset heading into the 2024 season, discussed the ...

Arizona Cardinals running back James Connor joins 'The Insiders' for an exclusive interview on Sept. 18. Former New York ...

Given that the calf strain to 49ers running back Christian McCaffrey suddenly and unexpectedly became an Achilles tendon, too ...

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

The San Francisco 49ers won’t have wide receiver Deebo Samuel for a couple weeks because of a calf injury he sustained late ...

Head coach Kyle Shanahan discussed running San Francisco's offense without RB Christian McCaffrey and WR Deebo Samuel Sr., ...

Just keep in mind a loss last year in Minnesota was part of the 49ers’ path to the Super Bowl: Without Deebo Samuel and ...

The 49ers offense will look so much different without Christian McCaffrey and Deebo Samuel. Enter rookie wide receiver Jacob ...

When you lose a game like the San Francisco 49ers did on Sunday in Minnesota, and when you are dealing with the injuries the ...