The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle ...

The San Francisco 49ers started off Week 3 on the right foot. After absences and limited participations littered their first ...

Defensive coordinator Nick Sorensen and run game coordinator and offensive line coach Chris Foerster reviewed the 49ers ...

San Francisco 49ers tight end George Kittle may miss Week 3's matchup with the Los Angeles Rams after missing Thursday's ...

San Francisco 49ers tight end George Kittle might miss Week 3's game with a hamstring. View the 49ers TE depth chart inside.

With McCaffrey and Samuel out, Rams brace for 49ers' cunning tactics. Kobie Turner stresses the need for execution.

Already without two of their most important players, the San Francisco 49ers added two more key names to the injury report ...

Tight end George Kittle (hamstring) and cornerback Charvarius Ward (knee/hamstring) did not practice Thursday after they were ...