Researchers successfully use a nonviral, piggyBac transposon system to introduce a transgene into cynomolgus monkeys.

Researchers in Japan have successfully used a nonviral piggyBac transposon system to introduce transgenes into cynomolgus monkeys, overcoming limitations of traditional virus-based methods. This ...

In neurons expressing a piggyBac A53T-α-synuclein transgene the scientists found two different types of aggregate (image below). Type I inclusions contained a lipid-rich mix of vesicular structures ...

Dr. Molly Duman Scheel, from the Indiana University School of Medicine – South Bend, and Dr. Corey Brizzee, from Demeetra discuss advanced gene editing technologies to create scalable and eco ...

Cytomed Therapeutics Ltd. has signed a memorandum of understanding (MOU) with Hangzhou CNK Therapeutics Co. Ltd. allowing Cytomed to utilize CNK's Piggybac technology to permanently graft the chimeric ...

We have developed novel piggyBac transposon (PB) -based CAR-T cells with favorable characteristics and durable antitumor efficacy against solid malignancies. A GMP-compliant manufacturing process ...

Poseida is a clinical-stage biopharmaceutical company focused on developing cell and gene therapies based on its proprietary platforms, including piggyBac, Cas-CLOVER, and nanoparticle technologies.

PiggyBac transposons arrived into our species by horizontal transfer -- similar to how some viruses can integrate their genome into our DNA.

The original piggyBac transposase PBase or the mouse codon-optimized version mPB and the construct to insert, contained in the piggyBac transposon, were introduced by in utero electroporation at ...