Gut-Brain Connection. People who have CD83+ microglia in their brains also have HCMV (top left) and IgG4 (top right) in their ...

The easiest way to track down "when" in a chronic disorder like AD is with the causal quartet, those carrying disease-causing mutations in APP, PSEN1, PSEN2 and SORL1, and, as you expand, including ...

The first round of a debate is most useful for isolating the crux. I therefore kindly ask for one more public round. This would be most beneficial, not just for me, but also for the many Alzforum ...

Notably, this coupling crumbles with age in mice. Restoring it not only bolstered neuronal energy reserves, but also strengthened synaptic signaling and counteracted memory loss in old animals.

• PhD, Yonsei University College of Medicine, Seoul, Korea 2008 • MS, Yonsei University College of Medicine, Seoul, Korea 2000 • MD, Yonsei University College of Medicine, Seoul, Korea 1997 ...

While all three genotypes of mice performed similarly to wild-type animals on multiple behavioral and spatial memory tests, ...

This letter was prompted by your recent perspective paper and the responses it provoked in an Alzforum discussion. Generally, my comments are offered with the intellectual humility required when ...

Of the 20,000+ human genes, none has greater influence on late-onset Alzheimer’s disease than APOE. But why do certain variants of this lipid transporter protect the brain, while others endanger it? A ...

Sixty percent said they would take a disease-modifying treatment if it provided three additional years of independence, compared to 45 percent for a treatment offering six months. These numbers varied ...

Some people’s brains age faster than average, some slower. Scientists quantify this “brain age gap” by subtracting a person’s chronological age from their brain’s biological age. Because aging brains ...