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  1. CX3C motif chemokine receptor 1 - Wikipedia

    CX3CR1 is integral membrane protein formed by 355 amino acids with molecular weight around 40 kDa, which consist of three distinguishable segments: extracellular, transmembrane and …

  2. CX3CR1 Gene - GeneCards | CX3C1 Protein | CX3C1 Antibody

    Mar 30, 2025 · CX3CR1 (C-X3-C Motif Chemokine Receptor 1) is a Protein Coding gene. Diseases associated with CX3CR1 include Macular Degeneration, Age-Related, 12 and …

  3. Tissue-specific Role of CX3CR1 Expressing Immune Cells and Their ...

    Chemokine (C-X3-C motif) ligand 1 (CX3CL1, also known as fractalkine) and its receptor chemokine (C-X3-C motif) receptor 1 (CX3CR1) are widely expressed in immune cells and …

  4. T-cell CX3CR1 expression as a dynamic blood-based biomarker of …

    Mar 3, 2021 · Recently, CX3C chemokine receptor 1 (CX3CR1) was found to be a marker of T-cell differentiation, where CX3CR1 + CD8 + T cells were the progeny of CX3CR1 − CD8 + T …

  5. The Chemokine Receptor CX3CR1 Defines Three Antigen ... - Cell …

    Dec 20, 2016 · Gerlach et al. (2016) demonstrate that CX3CR1 identifies three distinct CD8+ effector and memory T cell (Tmem) subsets. CX3CR1 correlated with the degree of effector …

  6. CX3CR1 C-X3-C motif chemokine receptor 1 [ (human)]

    CX3CR1 is a potential biomarker of immune microenvironment and prognosis in epithelial ovarian cancer. Validating Fractalkine receptor as a target and identifying candidates for drug …

  7. Cx3CR1 Expression Identifies Distinct Macrophage Populations

    Jul 1, 2019 · We show Cx3CR1 eGFP-hi macrophages in skin wounds are derived from long-term tissue-resident macrophages and predominantly exhibit an alternative activation state, …

  8. CX3CR1+CD8+ T cells: Key players in antitumor immunity

    Oct 8, 2024 · CX3CR1 functions as the specific receptor for the chemokine CX3CL1, demonstrating expression across a broad spectrum of immune cells. This underscores its …

  9. The CX3CL1-CX3CR1 chemokine axis can contribute to tumor …

    CX3CL1 secreted in the tumor microenvironment serves as a chemoattractant playing a critical role in metastasis of CX3CR1 expressing cancer cells. CX3CR1 can be expressed in both …

  10. CX3CR1 differentiates F4/80low monocytes into pro-inflammatory F4 ...

    Oct 10, 2018 · The precise roles of CX3CR1 in the liver have been investigated but not clearly elucidated. Here, we investigated the roles of CX3CR1 in hepatic macrophages and liver injury.