HHV-6A, 6B, and 7: pathogenesis, host response, and clinical disease
Feb 27, 1996 · HHV-6 and HHV-7 are ubiquitous, and more than 90% of adults have antibody to both viruses. These viruses have extensive homology and belong to the β-herpesvirus subfamily. The genome of HHV-6A is 159 321 bp in size, has a base composition of 43% G + C, and contains 119 open reading frames.
Update on human herpesvirus 7 pathogenesis and clinical aspects …
May 8, 2024 · Inoculating mice with a mouse-specific roseolovirus closely related to HHV-6 and HHV-7 (e.g., murine roseolovirus or MRV) might be an interesting substitute to broaden insights into HHV-7 immunopathogenesis .
HHV-6A, 6B, and 7: immunobiology and host response
The discoveries of Human herpesvirus 6 variant A (HHV-6A), Human herpesvirus 6 variant B (HHV-6B) and Human herpesvirus 7 (HHV-7) followed the development of methods for activation and long-term culture of peripheral blood T lymphocytes.
Human Herpesviruses 6, 7, and 8 From a Dermatologic Perspective
Three recently discovered members of the human herpesvirus (HHV) family are HHV-6, HHV-7, and HHV-8. The closely homologous HHV-6 and HHV-7 are ubiquitous, with nearly universal prevalence in persons older than 6 years.
Human betaherpesvirus 7 - Wikipedia
Human betaherpesvirus 7 (HHV-7) is one of nine known members of the Herpesviridae family that infects humans. HHV-7 is a member of Betaherpesvirinae, a subfamily of the Herpesviridae that also includes HHV-6 and Cytomegalovirus (HHV-5 or HCMV).
Herpes Virus Type 6 - StatPearls - NCBI Bookshelf
Aug 8, 2023 · Though the most common manifestation of human herpesvirus 6 (HHV-6) is the rash exanthema subitum, also called roseola infantum, HHV-6 has been known to establish a more threatening infection in immunocompromised individuals.
Human herpesvirus 7 infection - UpToDate
Oct 30, 2023 · Its linear, double-stranded DNA genome of about 145 kb shows homologies to human herpesvirus 6 (HHV-6) and cytomegalovirus (CMV). Mature HHV-7 particles measure 170 nm in diameter, with nucleocapsids of 90 to 95 nm and a tegument of approximately 30 nm [ 2 ].
Human Herpesviruses 6A, 6B, and 7 | Microbiology Spectrum
Human roseoloviruses include three different species, human herpesviruses 6A, 6B, and 7 (HHV-6A, HHV-6B, HHV-7), genetically related to human cytomegalovirus. They exhibit a wide cell tropism in vivo and, like other herpesviruses, induce a lifelong latent infection in humans.
Update on Human Herpesvirus 6 Biology, Clinical Features, and …
The Betaherpesvirinae human cytomegalovirus (HCMV), HHV-6, and HHV-7 have a less-confined cell tropism, and their clinical spectra are still being defined. HCMV congenital infection is a major cause of hearing loss and mental retardation.
Human Herpesvirus 6 Infection and Diagnostics - ScienceDirect
May 1, 2022 · Human herpesvirus 6 (HHV-6) causes primary infection in early childhood and establishes lifelong latency in its host. Reactivation of HHV-6, especially in immunosuppressed patients, has been associated with a variety of clinical complications.